HyperSol C18-AQ – Chromosep

Inquiry

The HyperSol® C18-AQ column is a specialized 100% aqueous-compatible C18 phase designed to deliver superior performance for highly polar and water-soluble compounds. Featuring advanced endcapping technology, it maintains excellent peak shapes for polar, acidic, and basic analytes while preventing phase collapse under high aqueous mobile phase conditions. Compared to the standard HyperSol® C18, the C18-AQ phase is less retentive for non-polar compounds but provides significantly enhanced retention for hydrophilic and water-soluble molecules, making it ideal for challenging aqueous-based separations.Engineered for exceptional batch-to-batch and column-to-column reproducibility, HyperSol® C18-AQ ensures consistent, high-quality chromatographic results across applications. Its robust silica chemistry and optimized surface treatment enable excellent stability and reproducibility even with 100% aqueous mobile phases. Perfect for the analysis of polar, acidic, basic, and water-soluble compounds that are typically difficult to retain on traditional C18 columns, HyperSol® C18-AQ is the column of choice for laboratories requiring reliable, high-resolution performance under fully aqueous conditions.

Column Material Specifications Comparison

Parameter	Value 1	Value 2
Particle Size (µm)	3	5
Pore Size (A°)	120	120
Surface Area (m2/g)	320	320
Carbon Load (%)	12	12
End Capping	Yes	Yes
pH Stability	2-10	2-10

Ordering Information

Particle Size (µm)	3	5
Dimension (mm)	P/N
300 X 4.6	-	HY185030046-A
300 X 4.0	-	HY185030040-A
250 X 4.6	HY183025046-A	HY185025046-A
250 X 4.0	HY183025040-A	HY185025040-A
150 X 4.6	HY183015046-A	HY185015046-A
150 X 4.0	HY183015040-A	HY185015040-A
150 X 3.0	HY183015030-A	HY185015030-A
150 X 2.1	HY183015021-A	HY185015021-A
125 X 4.6	HY183012546-A	HY185012546-A
125 X 4.0	HY183012540-A	HY185012540-A
125 X 3.0	HY183012530-A	HY185012530-A
125 X 2.1	HY183012521-A	HY185012521-A
100 X 4.6	HY183010046-A	HY185010046-A
100 X 4.0	HY183010040-A	HY185010040-A
100 X 3.0	HY183010030-A	HY185010030-A
100 X 2.1	HY183010021-A	HY185010021-A
75 X 4.6	HY183007546-A	HY185007546-A
50 X 4.6	HY183005046-A	HY185005046-A
50 X 4.0	HY183005040-A	HY185005040-A
50 X 3.0	HY183005030-A	HY185005030-A
50 X 2.1	HY183005021-A	HY185005021-A