ChromX® CN represents a revolutionary breakthrough in modern chromatographic technology, meticulously engineered with an advanced monomeric propylcyano (CN) bonded phase featuring complete endcapping to deliver exceptional analytical performance across diverse applications. This innovative versatile column operates seamlessly in both normal-phase and reverse-phase modes, providing scientists and analytical chemists with superior high-resolution separations of complex biological molecules, pharmaceutical compounds, peptides, proteins, and organic substances spanning the entire polarity spectrum from highly hydrophilic to moderately hydrophobic analytes.The unique intermediate polarity of the cyano functional group positions ChromX® CN as an ideal complementary phase between traditional alkyl-bonded columns (C18, C8) and bare silica or amino phases, offering distinctive selectivity mechanisms including dipole-dipole interactions, hydrogen bonding capabilities, and π-π electron interactions with aromatic compounds.