The CS 1521 UHPLC System is designed to deliver precision, efficiency, and convenience through its advanced integrated loop automatic sampler, ensuring lossless sampling and reliable performance even for small-volume and micro-level analyses. The system features a high-efficiency contact cooling system capable of reaching 4°C to room temperature within 30 minutes, maintaining sample stability and integrity throughout the analysis. With an overlapping sampling function, it eliminates idle time between injections, achieving faster sampling cycles and improved productivity. The 4× sample tray design accommodates up to 216 (54×4) or 384 (96×4) vials, providing high-throughput operation for demanding laboratory workflows. To ensure purity and prevent carryover, the system supports multi-solvent cleaning options and is equipped with durable, high-strength sampling needles for long-term performance. Together, these innovations enable smooth, rapid, and accurate sample handling—delivering a truly seamless and efficient UHPLC experience.